Transition-Metal-Catalyzed Regioselective Hydroselenation of Acetylenes with Selenols

摘要

A highly regioselective hydroselenation of terminal acetylenes with benzeneselenol is effectively catalyzed by palladium acetate in pyridine,providing the corresponding Markovnikov adducts in high yields predominantly.Very recently,the transition-metal-catalyzed reactions of organosulfur compounds have been growing,and highly selective transformations of organosulfur compounds have been developed by using transition-metal-catalysts.In contrast,examples of transition-metal-catalyzed reactions of organoselenium compounds are still rare,because organoselenium compounds bind transition-metal-catalysts much more strongly compared with the corresponding sulfur compounds,and make the catalytic reactions ineffective.