The nuances of serum neutralization assays viral diseases

摘要

During the immune response to viral infection, a host produces neutralizing antibody that binds to viral antigens and has varying abilities to prevent initiation of host cell infection. Neutralization assays, also referred to as virus neutralization or serum neutralization (SN) assays, are available for the detection of antibodies to several viral diseases, such as pseudorabies virus (PRV), transmissible gastroenteritis virus (TGEV), pestiviruses (BVDV and classical swine fever virus) and influenza Avirus.