Antisense homology boxes coincide with the 'hot spot' regions predicted by resonant recognition theory

摘要

Recent findings indicate that two novel theories, the Molecular Recognition Theory (MRT) based on the structure of the genetic code and on a novel motif termed antisense homology box, found in proteins and the Resonant Recognition Model, (RRM theory) based on resonant energy distribution of delocalised electrons between classes of proteins having similar functions may have common roots. The authors found that in contrast to a statistically expected 20% of overlap in the regions involved in the antisense homology boxes and hot "spots" predicted by RRM there is more than 60% prevalence of co-localization in proteins analyzed so far.