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RISK CHARACTERISATION OF SALMONELLA TYPHIMURIUM FROM CONSUMPTION OF IRISH FRESH PORK SAUSAGES

机译:食用爱尔兰新鲜猪肉香肠引起鼠伤寒沙门氏菌的风险特征

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A second-order simulation model was built to estimate the risk of Salmonella Typhimurium associated with the consumption of Irish fresh pork sausages using the results from a previous exposure assessment model and an Irish consumption database. To select appropriate hazard characterisation models, an appraisal of the current dose-response models fitted from available feeding trials data and outbreaks data was conducted. Using an infection and an illness dose-response model of the exponential type, for an infection end-point, the mean annual risk in an Irish sausage consumer was estimated to be 8.54×10~(-5) (95% CI: 2.41×10~(-5)-2.85×10~(-4)), or 192.8 expected infections per annum (95% CI: 24-695), while for an illness end-point, the risk parameters were lower at 7.68×10~(-6) (95% CI: 2.22×10~(-6)-2.54×10~(-5)), or 18.0 expected cases per annum (95% CI: 2-66). While results of the model highlighted the importance of the consumer education through advise of sufficient cooking and basic instructions regarding cold storage and shelf life, with some 'strong' assumptions, it was further estimated that the fresh pork sausage may have a plausible contribution of 30% to the total cases of salmonellosis within the pork sources.
机译:使用先前的暴露评估模型和爱尔兰消费数据库的结果,建立了一个二阶模拟模型来估计鼠伤寒沙门氏菌与爱尔兰新鲜猪肉香肠消费相关的风险。为了选择合适的危害特征模型,根据可用的喂养试验数据和暴发数据对当前的剂量反应模型进行了评估。使用感染和指数型疾病剂量反应模型,对于感染终点,爱尔兰香肠消费者的年平均风险估计为8.54×10〜(-5)(95%CI:2.41× 10〜(-5)-2.85×10〜(-4)),或每年预期感染192.8(95%CI:24-695),而对于疾病终点,风险参数较低,为7.68×10 〜(-6)(95%CI:2.22×10〜(-6)-2.54×10〜(-5))或每年18.0个预期病例(95%CI:2-66)。尽管该模型的结果通过提供足够的烹饪知识和有关冷藏和保质期的基本说明(并带有一些“强烈”的假设)强调了进行消费者教育的重要性,但据估计,新鲜猪肉香肠的贡献可能为30占猪肉来源中沙门氏菌病总数的百分比。

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