Numerical study of local hemodynamics in cuffed distal end-to-side anastomoses and correlation to intimal hyperplasia

摘要

Flow dynamical effects in anatomically realistic cuffed graft anastomoses models are analyzed applying computer simulation. The numerical results are compared to clinical and experimental observations on intimal thickening in the anastomotic region. The study concentrates on local hemodynamics in a bypass configuration of the Miller-cuff type, where a cuff of autologous vein is interposed between the graft and the host artery.