ASYMMETRICAL FLOW FIELD-FLOW FRACTIONATION: A NEW APPROACH TO ANALYSIS OF HIGH-MOLECULAR WEIGHT PROTEIN AGGREGATES?

机译：非对称流场分馏：分析高分子量蛋白聚集体的新方法？

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The fractionation of protein samples in monomer, dimer and high-molecular weight aggregates has been performed via asymmetrical flow field-flow fractionation (AFFFF). Molar masses were determined on-line by multi-angle laser-light scattering (MALLS). The separation of monomers and aggregates in pharmaceutically relevant protein samples was performed.

机译：蛋白质样品在单体，二聚体和高分子量聚集物中的分离已通过不对称流场-流分离法（AFFFF）进行。摩尔质量是通过多角度激光散射（MALLS）在线确定的。在药物相关蛋白质样品中进行单体和聚集体的分离。

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来源
《International symposium on controlled release of bioactive materials;Consumer diversified products conference》|2001年|p.900-901|共2页
会议地点 San Diego CA(US);San Diego CA(US)
作者
W. Fraunhofer; C. Schroer; M. Tschoepe; G. Winter;
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Department of Pharmaceutics and Bio-pharmaceutics Ludwig-Maximilians-University D-81377 Munich Germany;

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关键词
asymmetrical flow field-flow fractionation; absolute molecular mass characterization; multi-angle laser light scattering; protein aggregates;

机译：非对称流场-流分离绝对分子量表征多角度激光散射蛋白质聚集体;

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专利

1. Asymmetrical flow field-flow fractionation method for the analysis of submicron protein aggregates [J] . HaweA., RomeijnS., FilipeV., Journal of pharmaceutical sciences. . 2012,第11期

机译：非对称流场-流分离方法分析亚微米蛋白质聚集体
2. Characterization of oat proteins and aggregates using asymmetric flow field-flow fractionation [J] . Runyon J.R., Nilsson L., Alftrén J., Analytical and bioanalytical chemistry . 2013,第21期

机译：使用不对称流场-流分馏法表征燕麦蛋白质和聚集体
3. Characterization of oat proteins and aggregates using asymmetric flow field-flow fractionation [J] . J. Ray Runyon, Lars Nilsson, Johan Alftrén, Analytical and Bioanalytical Chemistry . 2013,第21期

机译：使用不对称流场-流分馏法表征燕麦蛋白质和聚集体
4. Characterization of Protein and Protein Aggregates Using Temperature Controlled Hollow Fiber Flow Field-Flow Fractionation [C] . Trevor Havard, Florian Meier, Soheyl Tadjiki, PEGS . 2015

机译：使用温控中空纤维流场分级的蛋白质和蛋白质聚集体的表征
5. Development of asymmetrical flow field-flow fractionation for the characterization of proteins, protein aggregation, and nanoparticles [D] . Bria, Carmen R. M. 2016

机译：非对称流场-流分离技术的发展，用于表征蛋白质，蛋白质聚集和纳米颗粒
6. Revisiting the dynamics of proteins during milk powder hydration using asymmetric flow field-flow fractionation (AF4) [O] . Anouk Lie-Piang, Mats Leeman, Alejandra Castro, 2021

机译：使用不对称流场 - 流量分级（AF4）重新审视奶粉水合过程中蛋白质的动态
7. Fluorescence-labelling for analysis of protein in starch using asymmetrical flow field-flow fractionation (AF4) [O] . Yeongsuk Yoo, Jaeyeong Choi, Claudia Zielke, 2017

机译：荧光标记用于使用不对称流场流动分馏（AF4）淀粉中蛋白质分析的荧光标记（AF4）
8. Evaluation of field-flow fractionation for molecular weight characterization of polymeric materials. Final report. [R] . Fuller, E. N. 1992

机译：评价用于聚合物材料分子量表征的场流分级。总结报告。

ASYMMETRICAL FLOW FIELD-FLOW FRACTIONATION: A NEW APPROACH TO ANALYSIS OF HIGH-MOLECULAR WEIGHT PROTEIN AGGREGATES?

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