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EXPERIMENTAL STUDY OF THE VASCULAR DYNAMICS OF A SACCULAR BASILAR ANEURYSM

机译:囊状基底动脉瘤血管动力学的实验研究

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摘要

A majority of patients who suffer hemorrhaging as a result of a ruptured cerebral aneurysm experience reduced quality of life, long term brain damage, or death. Improved understanding of the flow patterns in cerebral aneurysms will lead to better techniques for their detection and treatment. Experiments are conducted in a generic flow phantom to characterize the basic behavior of blood flow in basilar saccular aneurysms. The test setup models a saccular aneurysm that forms at the bifurcation of the basilar artery into the Circle of Willis. Three input flow conditions are tested: a physiological flow waveform obtained from Kato (2002) [1] and two steady flow conditions corresponding to the peak and mean flow rates of the physiological flow waveform. Steady cases are examined to study the effect of increasing Reynolds number on the flow and the pulsatile case to quantify unsteady effects. The results reveal highly three dimensionalflow patterns within the aneurysm. Velocity and vorticity fluctuations are extracted to investigate the nature of the unsteady flows. Wall shear stress is estimated around the aneurysm dome to examine its role in wall weakening and failure.
机译:由于脑动脉瘤破裂而导致出血的大多数患者的生活质量下降,长期脑损伤或死亡。更好地了解脑动脉瘤的血流模式将导致更好的技术来对其进行检测和治疗。在通用流动模型中进行实验,以表征基底囊状动脉瘤中血流的基本行为。该测试装置模拟了在基底动脉的分叉处进入威利斯环形成的囊状动脉瘤。测试了三个输入流量条件:从加藤(2002)[1]获得的生理流量波形和对应于生理流量波形的峰值和平均流量的两个稳定流量条件。研究了稳态情况,以研究增加雷诺数对流量的影响,以及脉动情况以量化不稳定影响。结果显示动脉瘤内的高度三维流型。提取速度和涡度波动以研究非稳态流动的性质。估计在动脉瘤穹顶周围的壁切应力,以检查其在壁弱化和衰竭中的作用。

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