FRUCTOOLIGOSACCHARIDE HAVING HIGH KESTOSE CONTENT AND APPLICATION THEREOF

摘要

The present invention relates to the field of biotechnology, and specifically discloses fructooligosaccharide having high kestose content and an application thereof. In the fructooligosaccharide having high kestose content in the present invention, the mass percentage of kestose among dry matter is greater than 80%, and the mass percentage of kestose in the fructooligosaccharide is more than 90%. The fructooligosaccharide having high kestose content in the present invention can increase Akkermansia muciniphila, Bifidobacterium, Lactobacillus and metabolite short-chain fatty acids thereof in rodent fecal and cecal contents, can increase the water content in rat feces to achieve a laxative effect, and can also enhance the secretion of γ-interferon from human peripheral blood lymphocytes and passage cells thereof, and inhibit inflammatory responses of intestinal epithelial cells induced by EHEC. In addition, the fructooligosaccharide having high kestose content in the present invention is helpful for preventing, improving or treating obesity, type 2 diabetes, Crohn's disease, atopic dermatitis, respiratory system infection and other diseases.