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NLRP3 NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF

机译:NLRP3 NLRP3炎症小体抑制剂及其用途

摘要

The present invention relates to an NLRP3 inflammasome inhibitor and its use for the treatment of NLRP3 inflammasome-mediated inflammatory diseases, and more particularly, to a compound having an excellent inflammasome inhibitory effect, or a pharmaceutically or pharmaceutically acceptable salt thereof. It provides NLRP3 inflammasome inhibitors, pharmaceutical compositions for preventing or treating NLRP3 inflammasome-mediated inflammatory diseases, health functional food compositions, and the like. The compound or a salt thereof significantly inhibits NLRP3 inflammasome activity, thereby effectively preventing, improving or treating various diseases caused by the activation of NLRP3 inflammasome.
机译:本发明涉及一种NLRP3炎症小体抑制剂及其用于治疗NLRP3炎症小体介导的炎症性疾病,更具体地说,涉及一种具有优异炎症小体抑制作用的化合物,或其药学或药学上可接受的盐。它提供NLRP3炎症小体抑制剂、用于预防或治疗NLRP3炎症小体介导的炎症性疾病的药物组合物、保健功能食品组合物等。该化合物或其盐显著抑制NLRP3炎症小体活性,从而有效预防、改善或治疗由NLRP3炎症小体激活引起的各种疾病。

著录项

  • 公开/公告号KR102430296B1

    专利类型

  • 公开/公告日2022-08-08

    原文格式PDF

  • 申请/专利权人 가톨릭대학교 산학협력단;

    申请/专利号KR20200122476

  • 发明设计人 이주영;최누리;

    申请日2020-09-22

  • 分类号C07D495/04;A23L33/10;A61K31/519;

  • 国家

  • 入库时间 2024-06-14 23:33:24

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