[Problem] To provide a tear fluid observation device, an information processing device, a program, and a learning model generation method with which it is possible for imaging of tear fluid to be carried out by a subject themselves and for the state of a subject eye to be easily ascertained. [Solution] This tear fluid observation device comprises: an imaging device for imaging a subject eye; a cover part having, on the inner side, a concave surface formed to face a region of the face of a subject that includes the subject eye; and a light-emitting body for irradiating the subject eye with light. The light-emitting body is a surface light source installed on the inner side of the cover part. The cover part is provided with a distal-end part configured to face the face of the subject, and a light guide part that is provided to a portion of the concave surface and that guides reflected light reflected by the surface of the subject eye toward the imaging unit.
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