OPIOID-FREE COMPOSITIONS FOR ANESTHESIOLOGICAL APPLICATIONS AND RELATED METHODS AND SYSTEMS

摘要

Opioid-free compositions, methods and systems are described. The compositions comprise magnesium salt, an alpha-2 agonist, a sodium channel inhibitor, and optionally an NMDA antagonist, a beta-blocker, and/or a corticosteroid, together with a pharmaceutically acceptable vehicle, carrier, or excipient. The compositions are suitable for peri-operative and intra-operative methods for a patient undergoing a medical or surgical procedure.