USE OF TERTIARY LYMPHOID STRUCTURES FOR THE PROGNOSIS OF DISEASE PROGRESSION OR TREATMENT IN CANCER

摘要

The present invention relates to an in vitro method for the prognosis of disease progression in a patient that suffers from or is at risk of developing cancer, said method comprising the step of determining, in a sample from said patient which is suspected to comprise neoplastic or cancerous tissue, whether or not the sample comprises a tertiary lymphoid structure (TLS), and prognosing disease progression, wherein the prognosis is an assessment regarding the likelihood of improved survival of the patient, and/or better clinical outcome of an immunotherapy.