A pharmaceutical composition for the prevention or treatment of inflammatory diseases containing mesenchymal stem cells as an active ingredient.

摘要

The present invention relates to a pharmaceutical composition for the prevention or treatment of inflammatory diseases, which comprises mesenchymal stem cells expressing HLA-A2 as an active ingredient. According to the present invention, mesenchymal stem cells expressing HLA-A2 on the surface suppress the secretion of the inflammatory cytokine TNF-a and increase the expression of the anti-inflammatory markers CD163 and Arg-1. , Thereby, the pharmaceutical composition containing mesenchymal stem cells as an active ingredient can be advantageously used to suppress inflammation or treat inflammatory diseases. [Selection diagram] Fig. 6