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DNA A complex consisting of branched DNA dendrimer and reducible polycations and a composition comprising the complex for enhancing immunity

机译:DNA是由支链DNA树枝状聚合物和可还原的聚合物组成的复合物,以及包含用于增强免疫力的复合物的组合物

摘要

The present invention relates to a composition comprising a branched DNA dendrimer and a reducing cationic polymer, a complex composed thereof, and an immune enhancing use thereof, wherein the combination of a DNA dendrimer and a reducing cationic polymer not only activates dendritic cells to promote an immune response, As a result, it was confirmed that the activated dendritic cells enhance the activation of T cells to improve the immune response, and by confirming that the immune response is enhanced and the anticancer effect is improved in an animal model, the DNA dendrimer of the branched structure and the reducing cationic polymer A composition comprising
机译:本发明涉及包含支链DNA树枝状聚合物的组合物和还原阳离子聚合物,其组成的复合物,以及其免疫增强用途,其中DNA树枝状聚合物和还原阳离子聚合物的组合不仅激活树突细胞以促进 结果,免疫应答结果证实,活化的树突细胞增强了T细胞的激活以改善免疫应答,并通过证实增强免疫应答并且在动物模型中提高了抗癌作用,DNA树枝状大分子 分枝结构和还原阳离子聚合物的组合物包含

著录项

  • 公开/公告号KR20210115528A

    专利类型

  • 公开/公告日2021-09-27

    原文格式PDF

  • 申请/专利权人 가톨릭대학교 산학협력단;

    申请/专利号KR20200031429

  • 发明设计人 이주영;강한창;오종한;

    申请日2020-03-13

  • 分类号A61K48;A61K31/711;A61K45/06;A61K47/59;

  • 国家 KR

  • 入库时间 2022-08-24 21:17:54

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