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MULTI-SITE SAMPLE HOLDERS, PCR STATION ASSEMBLIES, AND METHODS OF OPERATING PCR TESTING SYSTEMS

机译:多站点样品保持器,PCR站组件和操作PCR测试系统的方法

摘要

A multi-site sample holder for PCR processing. In one aspect, the multi-site sample holder includes a body with an inlet and outlet grooves formed alongside each other, a detection recess, and a cover interfacing with the body to form an inlet channel, a detection region interconnected to the inlet channel, and an outlet channel interconnected to the detection region. The detection region includes multiple sites and is configured to receive a PCR solution and replication occurs within the detection region via heating and cooling cycles. Thereafter, fluorescent emissions from tagged replicated DNA (or RNA) in the multiple sites may be individually (or in groups of less than all the sites) detected and measured. PCR station assemblies, PCR testing systems, and methods of operating a PCR testing systems are provided, as are other aspects.
机译:用于PCR加工的多场样品支架。 在一个方面,多场样品保持器包括具有彼此形成的入口和出口槽的主体,检测凹槽和与主体接合以形成入口通道的盖子,检测区域互连, 和互连到检测区域的出口通道。 检测区域包括多个位点,并且被配置为通过加热和冷却循环接收PCR溶液并在检测区域内发生复制。 此后,多个位点中的标记复制DNA(或RNA)的荧光发射可以单独(或以小于所有位点的组)单独(或以小于所有位点)。 提供PCR站组件,PCR测试系统和操作PCR测试系统的方法,也是其他方面。

著录项

  • 公开/公告号WO2021189065A1

    专利类型

  • 公开/公告日2021-09-23

    原文格式PDF

  • 申请/专利权人 SIEMENS HEALTHCARE DIAGNOSTICS INC.;

    申请/专利号WO2021US70133

  • 发明设计人 PATT PAUL;CHU DANIEL;

    申请日2021-02-08

  • 分类号B01L3;C12Q1/686;

  • 国家 US

  • 入库时间 2022-08-24 21:14:02

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