6 134- 134-Oxadiazol Derivative Compounds as Histone Deacetylase 6 Inhibitor and the Pharmaceutical Composition Comprising the same

摘要

The present invention relates to a novel compound having histone deacetylase 6 (HDAC6) inhibitory activity, an isomer or a pharmaceutically acceptable salt thereof, its use for the manufacture of a therapeutic agent, a pharmaceutical composition containing the same, and It relates to a method of treatment using the composition, and a method for preparing the same. The novel compound according to the present invention, an isomer thereof or a pharmaceutically acceptable salt thereof has a histone deacetylase 6 (HDAC6) inhibitory activity, and has cancer, inflammatory disease, autoimmune disease, neurological or degenerative neurological disease. It is effective for the prevention or treatment of HDAC6-related diseases, including.