The present invention relates to the use of certain RNA sequences as drugs. The present invention particularly relates to the use of small nucleolar RNAs (snoRNAs), and the inventors of the present invention have found that snoRNAs are involved in the mechanism of aging. The snoRNAs of the present invention not only increase the stress resistance of the patient in particular, fight against the deleterious effects of aging, and typically prevent or treat degenerative diseases, laminopathy, diabetes, obesity or cancer, but also in general the patient can be used to extend the life of The snoRNAs of the present invention can also be used in the treatment of infertility. The present invention also relates to vectors, cells, genetically modified animals and compositions capable of expressing the snoRNA according to the present invention, and for the identification of molecules active in the prevention or treatment of conditions, conditions or disorders associated with the mechanism of aging. It relates to a method of using the mentioned product of the invention as a tool.
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