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snoRNA, COMPOSITIONS, AND USES

机译:snoRNA,组成和用途

摘要

To provide molecules available to stop mechanisms of aging and fight against harmful effects associated therewith, as tools that permit "aging well" without disease or discomfort generally associated with old age.SOLUTION: The present invention concerns small nucleolar RNAs (snoRNAs) having particular RNA sequences as a medicament. The RNA sequences are involved in mechanisms of aging, and can be used in particular to increase the stress resistance of a patient, to control harmful effects of aging, typically to prevent or treat a degenerative disease, a laminopathy, diabetes, obesity or a cancer, and generally to prolong the lifespan of a patient. The snoRNAs can also be used in treatment of infertility.SELECTED DRAWING: None
机译:提供可用于停止衰老机制并对抗与其相关的有害作用的分子,作为允许“良好衰老”而又不伴有通常与老年有关的疾病或不适的工具。解决方案:本发明涉及具有特定RNA的小核仁RNA(snoRNA)序列作为药物。 RNA序列参与衰老机制,并且可以特别地用于增加患者的抗逆性,控制衰老的有害作用,通常用于预防或治疗退行性疾病,椎板病,糖尿病,肥胖症或癌症。 ,通常可以延长患者的寿命。 snoRNAs也可用于治疗不育症。

著录项

  • 公开/公告号JP2020010707A

    专利类型

  • 公开/公告日2020-01-23

    原文格式PDF

  • 申请/专利权人 NINOVAX;

    申请/专利号JP20190169733

  • 发明设计人 JEAN-RENE MARTIN;

    申请日2019-09-18

  • 分类号C12N15/113;A61K31/7105;A61P3/10;A61P3/04;A61P25/28;A61P35;A61P43;A61P15/08;A61K35/76;A61K35/54;A61K35/38;A61K49;C12N15/63;C12N5/10;G01N33/50;G01N33/15;

  • 国家 JP

  • 入库时间 2022-08-21 11:36:35

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