首页> 外国专利> CROSS-IMMUNIZING ANTIGEN VACCINE AND METHOD FOR PREPARATION THEREOF

CROSS-IMMUNIZING ANTIGEN VACCINE AND METHOD FOR PREPARATION THEREOF

机译:交叉免疫抗原疫苗及其制备方法

摘要

The present invention provides a fusion polypeptide that induces a humoral immune response and a cellular immune response to a virus, containing antigens or fragments thereof of the following (a) and (b), and having an oligomerization activity:;(a) an antigen of the virus or a fragment thereof containing a B cell epitope conserved among subtypes of the virus; and(b) an antigen of the virus or a fragment thereof containing a T cell epitope conserved among subtypes of the virus(wherein the antigen(s) or the fragment(s) thereof of (a) and/or (b) have an oligomerization activity, or the fusion polypeptide further contains (c) a polypeptide having an oligomerization activity in addition to the antigens or the fragments thereof (a) and (b)).
机译:本发明提供一种融合多肽,其诱导体液免疫应答和对病毒的细胞免疫应答,含有以下(a)和(b)的抗原或其片段,并具有低聚活性:;(a)抗原病毒或其片段含有在病毒亚型中保守的B细胞表位;和(b)病毒的抗原或其片段,含有T细胞表位在病毒的亚型中保守(其中(a)和/或(b)的抗原或其片段具有低聚活性,或者融合多肽进一步含有(c)除抗原外或除抗原外还具有寡聚化活性的多肽其片段(a)和(b))。

著录项

  • 公开/公告号US2021069320A1

    专利类型

  • 公开/公告日2021-03-11

    原文格式PDF

  • 申请/专利号US201816956212

  • 发明设计人 KENJI SEKIKAWA;

    申请日2018-12-21

  • 分类号A61K39/145;C07K14/005;A61K39/12;A61P31/16;

  • 国家 US

  • 入库时间 2022-08-24 17:39:08

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号