Diaryl hydantoin compound

摘要

PROBLEM TO BE SOLVED: To provide a diallyl hydantoin compound including diarylthiohydantoin, a method for synthesizing them, and a method for using them in the treatment of hormone-resistant prostate cancer. A method for treating a hyperproliferative disorder, wherein the composition of the present invention is administered to a subject in need of such treatment, thereby treating the hyperproliferative disorder. Including, methods. The present invention provides a series of compounds having strong antagonistic activity with minimal agonistic activity against AR. [Selection diagram] None