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BASICALLY SUBSTITUTED 1,2,3-BENZOTRIAZINE-4(3H)-ONE DERIVATIVES AND PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BASICALLY SUBSTITUTED 1,2,3-BENZOTRIAZINE-4(3H)-ONE DERIVATIVES AND PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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机译:基本取代的1,2,3-苯并三嗪-4(3H)-一衍生物及其制备方法和包含它们的药物组合物
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摘要
The present invention pertains to new, pharmacologically valuable basically substituted 1,2,3-benzotriazine-4(3H)-one derivatives having excellent coronary dilator properties and which have the structural formula WHEREIN R' is a radical selected from the group consisting of a secondary aliphatic, cycloaliphatic or araliphatic amine containing two to 10 carbon atoms; or of a 5, 6 or 7-membered heterocyclic nitrogen base, which contains in the nucleus in addition to the nitrogen atom a corresponding number of methylene groups as well as an additional member selected from the group consisting of a nitrogen, an oxygen or a sulfur atom, said radical being bound via a nitrogen atom; R1 is an alkoxy group having one to four carbon atoms, which may be in the 6,7 or 6,7,8-position; R2 is an alkoxy group having one to four carbon atoms; m is an integer selected from 1, 2 and 3; and n is an integer selected from 2 and 3; and to processes for producing said derivatives.
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