首页> 外国专利> BASICALLY SUBSTITUTED 1,2,3-BENZOTRIAZINE-4(3H)-ONE DERIVATIVES AND PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

BASICALLY SUBSTITUTED 1,2,3-BENZOTRIAZINE-4(3H)-ONE DERIVATIVES AND PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

机译:基本取代的1,2,3-苯并三嗪-4(3H)-一衍生物及其制备方法和包含它们的药物组合物

摘要

The present invention pertains to new, pharmacologically valuable basically substituted 1,2,3-benzotriazine-4(3H)-one derivatives having excellent coronary dilator properties and which have the structural formula WHEREIN R' is a radical selected from the group consisting of a secondary aliphatic, cycloaliphatic or araliphatic amine containing two to 10 carbon atoms; or of a 5, 6 or 7-membered heterocyclic nitrogen base, which contains in the nucleus in addition to the nitrogen atom a corresponding number of methylene groups as well as an additional member selected from the group consisting of a nitrogen, an oxygen or a sulfur atom, said radical being bound via a nitrogen atom; R1 is an alkoxy group having one to four carbon atoms, which may be in the 6,7 or 6,7,8-position; R2 is an alkoxy group having one to four carbon atoms; m is an integer selected from 1, 2 and 3; and n is an integer selected from 2 and 3; and to processes for producing said derivatives.
机译:本发明涉及新的,具有药理学价值的,基本上取代的1,2,3-苯并三嗪-4(3H)-一衍生物,其具有优异的冠状动脉扩张剂性质,并且其结构式为R'是选自下组的基团:含有两个至十个碳原子的仲脂族,脂环族或芳脂族胺;或5、6或7元杂环氮碱,其在原子核中除氮原子外还包含相应数量的亚甲基,以及选自氮,氧或氢的其他成员硫原子,所述基团通过氮原子键合; R1是具有1-4个碳原子的烷氧基,可以在6,7或6,7,8-位; R2是具有1-4个碳原子的烷氧基; m是选自1、2和3的整数; n是选自2和3的整数;以及生产所述衍生物的方法。

著录项

  • 公开/公告号IL34508A

    专利类型

  • 公开/公告日1973-07-30

    原文格式PDF

  • 申请/专利权人 CASSELLA FARBWERKE MAINKUR AG;

    申请/专利号IL19700034508

  • 发明设计人

    申请日1970-05-12

  • 分类号A61K27/00;C07D55/08;

  • 国家 IL

  • 入库时间 2022-08-23 07:39:34

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