6-SUBSTITUTED AMINO-3-NITROIMIDAZO(1,2-B)PYRIDAZINES AND METHODS OF PREPARING THE SAME

摘要

The preparation of 6-substituted amino-3-nitroimidazo-[1,2-b]pyridazines by reacting a 6-amino or substituted amino-3-nitroimidazo[1,2-b]pyridazine with an acid chloride or acid anhydride, is described. Other methods of preparing 6-substituted amino-3-nitroimidazo[1,2-b]pyridazines are described. The compounds are useful for their antiprotozoal and particularly antitrichomonal and antiamebic activity in warm-blooded animals.