method for the preparation of a medicine, medicine and method for preparation of formed suitable medicinal links.

摘要

1512101 Piperazino-pyrimidines PRODUITS CHIMIQUES UGINE KUHLMANN 8 Aug 1975 [9 Aug 1974] 33132/75 Addition to 1434544 Heading C2C Novel compounds (II) (including salts thereof) in which Z represents an alkyl group having 1 to 4 carbon atoms, R 1 represents a hydrogen atom or a methyl or ethyl group, and R 2 represents a linear alkyl group having 3 to 6 carbon atoms, an allyl, hydroxyethyl or cycloalkyl group having 3 to 8 carbon atoms, a benzyl or p-methoxyphenyl group and the -NR 1 R 2 residue may represent a morpholino group, are made by condensing the appropriate amines with 2,4,6-trichloro-5-methylthio-pyrimidine in a two-step process. Pharmaceutical prearations having antiemetic, neuroleptic, spasmolytic, analgesic and antiserotonine actions contain (II) as active ingredient.