首页> 外国专利> Procedure for the production of 5-phenyl-1, 3, 4, 4a, 5, 9b-hexahidro-2H-indeno (1,2-c) pyridines. (Machine-translation by Google Translate, not legally binding)

Procedure for the production of 5-phenyl-1, 3, 4, 4a, 5, 9b-hexahidro-2H-indeno (1,2-c) pyridines. (Machine-translation by Google Translate, not legally binding)

机译:制备5-苯基-1、3、4、4a,5、9b-六氢-2H-茚并(1,2-c)吡啶的程序。 (通过Google翻译进行机器翻译,没有法律约束力)

摘要

Process for the production of 5-phenyl-1,3,4,4a, 5,9b-hexahydro-2H-indene [1,2-c] pyridines, of the general formula **(See formula)** wherein either R2 and R3 signify hydrogen or R2 signifies chlorine, bromine, fluorine or a lower alkyl radical and R3 signifies hydrogen, chlorine, bromine, fluorine or an alkyl, alkylthio or lower alkoxy radical or trifluoromethyl, and their addition salts acid, characterized in that of a compound of general formula **(See formula)** wherein R2 and R3 have the meaning indicated above and R1 means the methyl or benzyl radical, the methyl or benzyl radical is cleaved and, if desired, mixtures of the compounds in which the 4a/5 hydrogen atoms are trans and 4a/9b hydrogen atoms are trans, and where 4a/5 hydrogen atoms are trans and 4a/9b hydrogen atoms are cis, they are separated into their different isomers and/or compounds of formula I obtained are transformed into their acid addition salts. (Machine-translation by Google Translate, not legally binding)
机译:制备具有通式**(参见通式)**的5-苯基-1,3,4,4a,5,9b-六氢-2H-茚[1,2-c]吡啶的方法,其中R2 R3表示氢或R2表示氯,溴,氟或低级烷基,R3表示氢,氯,溴,氟或烷基,烷硫基或低级烷氧基或三氟甲基及其加成盐,其特征在于通式**(参见式)**的化合物其中R2和R3具有上述含义,R1表示甲基或苄基,甲基或苄基被裂解,如果需要,还可混合其中4a表示的化合物的混合物/ 5个氢原子为反式且4a / 9b氢原子为反式,且其中4a / 5氢原子为反式且4a / 9b氢原子为顺式,它们被分离成不同的异构体和/或将得到的式I化合物转化变成酸加成盐(通过Google翻译进行机器翻译,没有法律约束力)

著录项

  • 公开/公告号ES404878A1

    专利类型

  • 公开/公告日1976-01-01

    原文格式PDF

  • 申请/专利权人 SANDOZ A.G.;

    申请/专利号ES19720404878

  • 发明设计人

    申请日1972-07-14

  • 分类号C07D;

  • 国家 ES

  • 入库时间 2022-08-23 02:30:51

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