Olefins hydroxylation to polyhydric alcohols - using hypochlorite in presence of osmium tetroxide

摘要

Olefinic cpds. in an aq. medium at a pH of =7 are oxidised in the presence of osmium tetroxide by an alkali(ne earth) metal hypochloride at -10-60 degrees C to form a dihydroxy addn. prod. of the olefinic cpd. The process requires small amts. of expensive osmium tetroxide. The olefin is opt. cyclic and is opt. substd. by hydroxyl, carboxy, carboxylic ester, carboxylic amide or halogen.