PROCESS FOR THE STEREOSELECTIVE PRODUCTION OF INTERMEDIATES IN THE SYNTHESIS OF PGE1 AND DERIVATIVES

摘要

1421555 Prostaglandin intermediates G D SEARLE & CO 1 March 1973 [17 March 1972] 53952/74 Divided out of 1421553 Heading C2C [Also in Division C3] Novel compounds of Formula III in which R=H or C 1-7 alkyl and RSP1/SP=tetrahydropyran-2-yl or 4-C 1-7 alkoxy-tetrahydropyran-4-yl, are prepared by contacting a compound of Formula II with aqueous chromous sulphate, acetate or perchlorate.