4-PHENYL-1,3-BENZODIAZEPINES AND METHODS OF PREPARING THE SAME

摘要

Compounds of the formula CHEM in which R and R1 are the same or different and each can be hydrogen, alkyl of from 1 to 3 carbon atoms, cycloalkyl- C-C3-alkyl, wherein the cycloalkyl radical has 3 - 6 carbon atoms, or aralkyl having up to 8 carbon atoms, X and Y are the same or different and each can be chlorine, bromine, fluorine, alkoxy or alkyl, each of from 1 to 3 carbon atoms, hydroxy, or trifluoromethyl, m is the integer 0, 1 or 2, n is the integer 0, 1,2 or 3, the optical antipodes thereof, physiologically acceptable salts thereof, and pharmaceutical compositions containing them. They are prepared by the cyclisation of compounds of the formula CHEM with a compound of the formula CHEM