首页> 外国专利> POWDER-MIXED COMPOSITION INCLUDING AMPHIFILE LIPID COMPONENTS AND, optionally, HYDROPHOBIC COMPONENTS, PROCEDURES FOR THE PREPARATION OF SAME, HYDRATIZED, LAYERED LIPID PHASES, PROCEDURES FOR THE PRODUCT

POWDER-MIXED COMPOSITION INCLUDING AMPHIFILE LIPID COMPONENTS AND, optionally, HYDROPHOBIC COMPONENTS, PROCEDURES FOR THE PREPARATION OF SAME, HYDRATIZED, LAYERED LIPID PHASES, PROCEDURES FOR THE PRODUCT

机译:粉末混合的成分,包括两性脂质成分和(可选)疏水成分,制备相同,水合,分层脂质相的程序,产品程序

摘要

The invention relates to a method for preparing a pulverulent mixture of amphiphilic lipidic constituents and possibly of hydrophobic constituents, as well as to a method for producing hydrated lipidic lamellar phases from the pulverulent mixture. The method comprises dissolving the amphiphilic lipidic constituents and the hydrophobic constituents in an appropriate solvent and then atomizing said solution in a flow of gaseous fluid to produce the pulverulent mixture. The mixture thus obtained is a homogeneous and very fine powder which can be very easily dispersed in a suitable aqueous dispersion medium to produce either slightly hydrated lipidic lamellar phases or highly hydrated lipidic lamellar phases such as liposomes useful in the pharmaceutical and cosmetic fields.
机译:本发明涉及一种制备两亲脂质成分和可能是疏水成分的粉状混合物的方法,并且涉及一种由该粉状混合物生产水合脂质层状相的方法。该方法包括将两亲脂质成分和疏水成分溶解在适当的溶剂中,然后在气态流体流中雾化所述溶液以产生粉状混合物。由此获得的混合物是均匀且非常细的粉末,其可以非常容易地分散在合适的水性分散介质中,以产生在药物和化妆品领域中有用的稍微水合的脂质层状相或高度水合的脂质层状相,例如脂质体。

著录项

  • 公开/公告号DK67783A

    专利类型

  • 公开/公告日1983-08-18

    原文格式PDF

  • 申请/专利权人 PARFUMS CHRISTIAN DIOR S.A.;

    申请/专利号DK19830000677

  • 发明设计人 REDZINIAK GERARD;MEYBECK ALAIN;

    申请日1983-02-16

  • 分类号B01J;B01F;A23J;A61K;

  • 国家 DK

  • 入库时间 2022-08-22 11:12:00

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