Procedure for the production of a preparation, Practice Safe against hepatitis, Factors of coagula - tion of Sange IX and X - or.

摘要

Procedure for the production of a preparation of Blood coagulation factor IX and X - or.Mix a Solution containing - factor and factor IX or X, a fraction of plasma or placental preferiblente with a soluble calcium salt, such as Calcium chloride or Calcium acetate at a concentration of 0.4 to 0.6 mol per Liter and eventually with 1 to 3 ml per Liter of at least one amino Acid, such as Glycine, and 20 to 60% by weight of a monosaccharide,Azucaralcohol oligosaccharide or as sucrose. Heated to a temperature between 60 and 100 degrees Celsius for a Time about 10 hours, maintaining a pH value of 6.5 to 8.0. The Preparation is used for intravenous infusion, preferably in the form of, for the therapy and prophylaxis of hemorrhage caused by deficiency of factor IX or X Factor.