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new derivatives piperidinici with property antiistaminiche antiallergiche and broncodilatatrici and process for their preparation
new derivatives piperidinici with property antiistaminiche antiallergiche and broncodilatatrici and process for their preparation
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机译:具有抗过敏药,抗过敏药和支气管扩张药的新衍生物哌啶乙腈及其制备方法
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摘要
Pharmaceutically useful compounds of the following formula: IMAGE wherein R1 represents hydrogen or hydroxy; R2 represents hydrogen; or R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is a positive whole integer of from 1 to 5; R3 is -CH3, -CH2OH, -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; and A and B are individually hydrogen or hydroxy; with the provisos that at least one of A or B is hydrogen and one of A or B is other than hydrogen when R3 is -CH3; and pharmaceutically acceptable acid addition salts thereof.
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机译:下式的药学上有用的化合物:其中R1代表氢或羟基; R 2代表氢;或者R1和R2一起在带有R1和R2的碳原子之间形成第二键; n为1到5的正整数。 R3是-CH3,-CH2OH,-COOH或-COO烷基,其中烷基部分具有1-6个碳原子并且是直链或支链的; A和B分别为氢或羟基;前提是当R 3为-CH 3时,A或B中的至少一个是氢,且A或B中的一个不是氢。及其药学上可接受的酸加成盐。
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