首页> 外国专利> Improvements to the subject matter of patent of invention no. 541,911 relating to Process for obtaining new amp;alpha;- (alkylaminopropionyl)-thiophen derivatives substituted in the thiophen ring

Improvements to the subject matter of patent of invention no. 541,911 relating to Process for obtaining new amp;alpha;- (alkylaminopropionyl)-thiophen derivatives substituted in the thiophen ring

机译:发明专利No.4的改进。 541,911与获得在噻吩环中取代的新的α-(烷基氨基丙酰基)-噻吩衍生物的方法有关

摘要

Improvements to the subject matter of patent of invention no. 541,911 relating to Process for obtaining new α- (alkylaminopropionyl)-thiophen derivatives substituted in the thiophen ring comprises reacting α (bromopropionyl)-thiophens of general formula II' with amines of general formula III', thus obtaining the new α-(alkylaminopropionyl)-thiophen derivatives substituted in the thiophen ring of general formula I' where X' is a radical other than hydrogen, preferably methyl or chlorine, and R' is a straight or branched alkyl radical, which can form pharmaceutically acceptable salts by treatment with corresponding acids. Having pharmacological application through its antidepressant effect. IMAGE
机译:发明专利No.4的改进。与获得在噻吩环中取代的新的α-(烷基氨基丙酰基)-噻吩衍生物的方法有关的541,911包括使通式II'的α(溴丙酰基)-噻吩与通式III'的胺反应,从而获得新的α-(烷基氨基丙酰基) -在通式I′的噻吩环中取代的-噻吩衍生物,其中X′是氢以外的基团,优选甲基或氯,并且R′是直链或支链烷基,其可以通过用相应的酸处理形成药学上可接受的盐。通过其抗抑郁作用具有药理应用。 <图像>

著录项

  • 公开/公告号ES8704922A2

    专利类型

  • 公开/公告日1987-07-01

    原文格式PDF

  • 申请/专利权人 FERRER INTERNACIONAL S.A.;

    申请/专利号ES19860552220

  • 发明设计人

    申请日1986-02-20

  • 分类号C07D333/20;A61K31/38;

  • 国家 ES

  • 入库时间 2022-08-22 07:17:06

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