FUSED AROMATIC OXAZEPINONES AND SULFUR ANALOGS THEREOF IN A METHOD OF COUNTERACTING HISTAMINE

摘要

419A-CIPFUSED AROMATIC OXAZEPINONES ANDSULFUR ANALOGS THEREOFABSTRACT OF THE INVENTIONAromatic-2,3-dihydro-1,4-oxazepin-5(4H)-ones andsulfur analogs thereof having the formulawhexein B and E are oxygen and/or sulfur, n is 1, 2 or3, Z is -NR1R2, 1H-pyrazol-l-yl ox 1H-imidazol-l-yl andR is loweralkyl, cycloalkyl or phenylloweralkyl havingantihistaminic application, a process for the preparationthereof, and intermediates therefor are disclosed.