The present invention concerns a portion of a conformational epitope of human immunodeficiency virus envelope gp120 comprising the sequence of the BH-10 subtype, not comprising more than 302 amino acids, and analogous sequences from human immunodeficiency virus gp120 isolates other than BH-10.;Such sequence can be employed in an anti-HIV-1 vaccine. The sequence can also be used in combination with amino acid sequences from (303-338) of the BH subtype of HIV-1, or analogous sequences from HIV-1 isolates other than BH-10.
展开▼
机译：本发明涉及人免疫缺陷病毒包膜gp120的构象表位的一部分，其包含序列<图像文件=“ IMGA0001.GIF” he =“ 13” imgContent =“ dna” imgFormat =“ GIF” wi =“ 89” /> 包含不超过302个氨基酸的BH-10亚型，以及来自BH-10以外的人类免疫缺陷病毒gp120分离株的类似序列。这种序列可用于抗HIV-1疫苗。该序列也可以与HIV-1的BH亚型的（303-338）氨基酸序列或BH-10以外的HIV-1分离株的类似序列结合使用。
展开▼
