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Azole derivatives, processes for their preparation, and uses thereof

机译:唑类衍生物,其制备方法及其用途

摘要

Azole derivative of the general formula (I) IMAGE in which A, L, O, R1, X, Y, Z and q have the meanings given, a process for their preparation, pharmaceutical preparations and the use of the compounds are described. Azole derivatives of the formula I where the symbols have, for example, the following meanings: R1 = (C2-C10)-alkyl Z = nitrogen X and Y = independently of one another CR2 L = -CH2- q = zero or 1 A = biphenyl radical which is substituted, for example, by R15 R2 = halogen or hydrogen R15 = SO2-NH-CO-OR6 and R6 = phenyl, are highly active antagonists of angiotensin II receptors.
机译:通式(I)的Azole衍生物,其中A,L,O,R 1,X,Y,Z和q具有给定的含义,其制备方法,药物制剂和其用途描述了化合物。式I的偶氮衍生物,其中的符号例如具有以下含义:R 1 =(C 2 -C 10)-烷基Z =氮X和Y彼此独立地表示CR 2 L = -CH 2- q =零或1 A =被例如R 15取代的联苯基R 2 =卤素或氢R 15 = SO 2 -NH-CO-OR 6和R 6 =苯基是血管紧张素II受体的高活性拮抗剂。

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