Reveals the trance forming growth factor 1 binding protein and this binding protein which were refined sufficiently the nucleotide array

摘要

Purified protein known as platelet TGF-β1-BP (transforming growth factor-β1-binding protein) is described. The protein is useful for purposes such as the production of antisera which is useful in identifying complexes containing the binding protein, as well as in formation of labeled probes itself. Also described is purified DNA which expresses the protein, as well as messenger RNA translated into the protein. The protein contains 16 epidermal growth factors (EGF) like repeats, and 3 repeats not found in other proteins. The DNA for the protein is found to contain consensus sequences for hydroxylation of asparagine/aspartic acid residues, and, in the purified protein beta hydroxylated asparagine residues were found.