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THERAPEUTIC AGENT FOR TREATING MENTAL DISORDER CONTAINING BENZOIMIDAZOLINE-2-OXO-1-CARBOXYLIC ACID DERIVATIVE

机译:包含苯并咪唑啉-2-氧代-1-羧酸衍生物的治疗精神错乱的治疗剂

摘要

PURPOSE: To provide an agent for the treatment of mental disorder or primary degeneration dementia and amnestic syndrome by using a specific benzimidazoline-2-oxo-1-carboxylic acid derivative as an active component. CONSTITUTION: This agent for the treatment of mental disorder, primary degeneration dementia and amnestic syndrome contains a benzimidazoline-2-oxo-1- carboxylic acid derivative of the formula I [R is H, a 1-6C alkyl, a 2-6C alkenyl or a 2-6C alkynyl; Y is O or NH; A is a group of the formula II ((n) is 0-3), the formula III, the formula IV or the formula V], its physiologically permissible acid addition salt or their solvated compounds as active component. The compound of the formula I is e.g. N-(endo-8-methyl-8-azabicyclo[3,2,1]oct-3-yl)-2,3- dihydro-2-oxo-1H-benzimidazole-1-carboxamide.
机译:目的:通过使用特定的苯并咪唑啉-2-氧-1-羧酸衍生物作为活性成分,提供治疗精神障碍或原发性变性痴呆和遗忘症的药物。组成:该药物用于治疗精神障碍,原发性变性痴呆和失忆综合症,其含有式Ⅰ的苯并咪唑啉-2-氧代-1-羧酸衍生物[R为H,1-6C烷基,2-6C烯基或2-6C炔基; Y为O或NH; A为式II((n)为0-3),式III,式IV或式V],其生理上允许的酸加成盐或它们的溶剂化化合物作为活性组分的基团。式I的化合物为例如甲基。 N-(内酯-8-甲基-8-氮杂双环[3,2,1]辛-3-基)-2,3-二氢-2-氧代-1H-苯并咪唑-1-羧酰胺。

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