method for preparing a 7 - (d - alpha - alpha (p hydroxyphenyl) acetamido) - 3 - (heterocyclylthiomethyl) - 3 - cefem - 4 - carboxylic acid derivative and a pharmaceutical preparation with antibacterial effect.

摘要

The novel compounds of the formula I, in which the substituents have the meaning given in Claim 1, are obtained by treating a suspension of an amphoteric cephalosporin of the formula II, or a solvate thereof, with an aldehyde of the formula R2-CHO. The condensation products which are obtained represent novel synthetic cephalosporins which can be used as anti-bacterial agents and also as feed additives for animals. IMAGE