Noninvasive method for quantitation of oxyhemoglobin saturation by near- infrared reflectance spectrophotometry

摘要

The degree of hemoglobin oxygenation in the blood vessels of the retina isetermined under conditions of dark-adaptation and light- adaptation by directing a beam of near-infrared light having a range of wavelengths from 700 to 100 nanometers at a blood vessel in the retina, measuring the intensity of the backscattered light from the blood vessel in the range from 700 to 800 nanometers at regularly spaced intervals of wavelength, such as 2 nanometers, and determining the degree of hemoglobin oxygenation by reference to a correlation between hemoglobin oxygen and light absorbance in the near-infrared spectral range.