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Liponucleosidos Dry Nucleosides, Process for their Preparation and compositions containing them with antiviral activity.
Liponucleosidos Dry Nucleosides, Process for their Preparation and compositions containing them with antiviral activity.
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机译:脂核苷干核苷,其制备方法和含有抗病毒活性的组合物。
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摘要
The invention provides a general formula (I): R1 is a saturated or unsaturated, unsaturated, straight-line or branch tar chain, containing up to 20 carbon atoms, which can be replaced once or more by 1 to 6 carbon atoms of phenyl, halogen and carbon atoms. R2 is a saturated or unsaturated, unsaturated, linear or separator tar chain, which contains up to 20 carbon atoms. One or more carbon atoms can be replaced optionally. Phenyl, halogen,There are 1 to 6 carbon atoms, commercial tar, 1 to 6 carbon atoms, oxygen carbides, 1 to 6 carbon atoms of hydrogen sulfide, 1 to 6 carbon atoms or 1 to 6 carbon atoms of tar, R3 hydrogen atoms or 1 to 6 carbon atoms of radical tar, which can be replaced by hydroxyl group. R4 is an atom. In hydrogen, a hydroxyl or amino group or an Amin group is replaced once or twice by a tar of 1 to 6 carbon atoms, R5 is a hydrogen atom, a hydroxyl or ammonia group, or an Amin group is replaced once or twice by a tar of 1 to 6 carbon atoms,X is a link in Valencia, or oxygen or sulfur atom, or sulfur or sulfur group, with the same meaning as X, so x and Y may be the same or different, Z is oxygen or sulfur atom, and its ceramic strength and physiologically acceptable salt containing acid and inorganic base. The present invention also provides procedures for the preparation of these antiviral lipolysis and pharmaceutical compounds, at least one of which is lipolysis.
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机译:本发明提供了通式(I):R1是饱和或不饱和,不饱和,直链或支链的焦油链,含有至多20个碳原子,其可以被苯基的1至6个碳原子取代一次或多次,卤素和碳原子。 R 2是饱和或不饱和,不饱和,线性或隔板的焦油链,其包含多达20个碳原子。一个或多个碳原子可以任选地被取代。苯基,卤素,有1至6个碳原子,商品焦油,1至6个碳原子,碳化氧,1至6个碳氢硫化物,1至6个碳原子或1至6个碳原子的焦油,R3氢原子或基团焦油的1至6个碳原子,可以被羟基取代。 R 4是原子。在氢中,羟基或氨基或Amin基团被1至6个碳原子的焦油取代一次或两次,R5是氢原子,羟基或氨基团,或Amin基团被1个碳原子取代一次或两次。 1-6个碳原子的焦油,X是巴伦西亚的一个键,或氧或硫原子,或硫或硫基,含义与X相同,因此x和Y可以相同或不同,Z为氧或硫原子,其陶瓷强度和含有酸和无机碱的生理上可接受的盐。本发明还提供了制备这些抗病毒脂解作用和药物化合物的方法,其中至少一种是脂解作用。
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