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Diphenylmethane derivatives, process for their production and their use for the displacement of iodothyronines from proteins which bind them

机译:二苯甲烷衍生物,其生产方法及其用于从与它们结合的蛋白质中置换碘代甲状腺素的用途

摘要

The present invention concerns compounds having the general formula I ##STR1## in which R.sup.1 denotes hydrogen or hydroxy,P PR. sup.2 denotes hydrogen or hydroxy,PPR.sup.3 denotes hydrogen or alkoxy,PPR.sup.4 denotes hydrogen, CO. sub.2 H, SO.sub.3 H, PO.sub.3 H.sub.2 or a salt of the corresponding acid, PPR.sup.5 denotes CO.sub.2 H, SO.sub.3 H, PO.sub.3 H.sub. 2 or a salt of the corresponding acid andPPR.sup.6 denotes alkoxy,PPtheir use for displacing iodothyronines from proteins binding them, as well as a method and reagent for the determination of iodothyronine in which such compounds are used.
机译:本发明涉及具有通式I的化合物,其中R 1表示氢或羟基。 sup.2表示氢或羟基,P = R 3表示氢或烷氧基,P = R 4表示氢,CO.sub.2 H,SO.sub.3 H,PO 3 H 2或相应酸的盐,

R 3表示CO 2 H,SO 3 H,PO 3。 3 H.sub。 2或相应的酸的盐表示,烷氧基,用于从与它们结合的蛋白质中置换碘代甲状腺素,以及测定使用此类化合物的碘甲状腺素。

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