PROTAMINO INSULIN COMPLEX, PHARMACEUTICAL COMPOSITION CONTAINING SUCH COMPLEX AND METHOD OF OBTAINING SAME AS WELL AS OBTAINING CRYSTALLINE PROTAMINO INSULIN

摘要

The present invention discloses various parenteral pharmaceutical formulations, which comprise: a monomeric insulin analog, zinc, protamine, and phenolic derivative. The analog formulations provide a prolonged duration of action. A process for preparing insulin analog-protamine formulations is also described.