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Device and method for conveying and separating a suspension with biological cells or micro-organisms

机译:用生物细胞或微生物输送和分离悬浮液的装置和方法

摘要

The device for conveying and separating a suspension with biological cells or micro-organisms in biological processes has a rotating separating element in a surrounding reaction space with a flow space which is in the form of a rotational gap, an inlet opening, an inner outlet opening for the cell-free medium, an outer through opening and an exit opening for the suspension. The distance R4 of the exit opening from the axis of rotation is greater than the distance R1 of the inlet opening, and the distance R3 of the through opening is greater than the distance R2 of the inner outlet opening. The suspension can thus be conveyed in the flow space and the cells efficiently separated at the same time. The device is particularly suitable for continuous operation with sensitive mammal cells.
机译:用于在生物过程中输送和分离带有生物细胞或微生物的悬浮液的装置在周围的反应空间中具有旋转的分离元件,该旋转的分离元件具有呈旋转间隙形式的流动空间,入口,内部出口对于无细胞培养基,有一个外部通孔和一个悬浮液出口。出口孔距旋转轴线的距离R4大于入口孔的距离R1,通孔的距离R3大于内部出口孔的距离R2。悬浮液因此可以在流动空间中被输送,并且细胞同时被有效地分离。该设备特别适合与敏感的哺乳动物细胞连续运行。

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