methods for their preparation from β'- unsubstituted tetrapyrrole macrocycle, β'- dihydroxy meso-substituted chlorin, iso bacteriochlorins, and bacteriochlorins, β, β

摘要

A beta , beta '-dihydroxy meso-substituted chlorin, bacteriochlorin or isobacteriochlorin compound having the formula (I) or (II): IMAGE (I) or IMAGE (II) wherein M is a metal. A novel method for synthesizing the compound of formula (I) or (II) comprises the steps of: a. osmylating a beta . beta '-unsubstituted, meso-substituted porphyrin to form an osmate ester at the beta , beta '-position, and b. reducing the osmate ester to form the corresponding beta , beta '-dihydroxy meso-substituted chlorin, bacteriochlorin or isobacteriochlorin of formula (I) or (II).