The process of preparing for the Silk Road

摘要

1. Preparation procedure of formula compound (I),Figure 1 shows 5 - [2-etoxi-5 - (4-methylpiperazin-1-il-sulfonil) FeNi] - 1-methyl-3-n-propil-1, 6-dihydro-7h-pirazol [4, 3-d] pirimidin-7-ona, which includes a cycle of a formula compound (II),As shown in Figure 2, bicycles are carried out under basic, neutral or acidic conditions. Specifically, it includes a procedure for recycling cyclohexane in the presence of a base (preferably in a solvent), hydrogen peroxide or peroxides, and then neutralizing the reaction mixture if necessary. When there is a pseudoacid or Lewis acid, choose in the solvent. In addition, an intermediary consisting of the general formula (V) (as shown in Figure 3) claims that:Or triethylamine dichloride hydrochloride or one of C1-4 asphalt. Formula compound (I) is useful for erectile dysfunction.