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Glucocorticoid enhancement of gene expression.

机译:糖皮质激素增强基因表达。

摘要

The present invention provides a method of increasing the cellular expression of a gene in a biological tissue after delivery of said gene to an animal, comprising the step of: administering to said animal a pharmacologically effective dose of a glucocorticoid in an amount sufficient to increase the cellular expression of said gene. Also provided is a various method of treating a pathophysiological state in a human by increasing cellular expression of a gene after delivery of said gene into a biological tissue of an animal in need of such treatment, comprising the step of: administering to said animal a pharmacologically effective dose of a glucocorticoid in an amount sufficient to increase the cellular expression of said gene.
机译:本发明提供了在将所述基因递送给动物后增加基因在生物组织中的细胞表达的方法,该方法包括以下步骤:向所述动物施用药理学有效剂量的糖皮质激素,其量足以增加所述糖皮质激素的量。所述基因的细胞表达。还提供了通过在将所述基因递送到需要这种治疗的动物的生物组织中之后增加基因的细胞表达来治疗人的病理生理状态的各种方法,包括以下步骤:对所述动物进行药理学给药。糖皮质激素的有效剂量,其量足以增加所述基因的细胞表达。

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