Process and a device for producing a transdermal therapeutic system for the administration of active substances to the skin in the form of a plane multichamber or multichamber-channel system

摘要

In a process for the production of a transdermal therapeutic system for the administration of active substances to the skin in the form of a plane multichamber or multichamber-channel system an active substance- containing layer is introduced between top layer and bottom layer; subsequently top and bottom layer are squeezed at individual and/or coherent sites under displacement of the intermediary sites of the active substance-containing layer and formation of active substance- containing chambers or channels, and at the same time or after that top layer and bottom layer are bonded permanently at the squeezed places.