METHOD FOR ISOLATION AND PURIFICATION OF CHONDROITIN SULFATE

摘要

PROBLEM TO BE SOLVED: To provide a technology which can supply chondroitin sulfate in large quantity and at low cost from a raw material of nosal cartilages of fishes, especially of salmon heads. ;SOLUTION: A technology to obtain the powder of chondroitin sulfate comprises the steps of: alkali-treating fish's nosal cartilages containing chondroitin sulfate, and optionally, treating it by means of proteolytic enzyme, thereby to give an aqueous solution containing chondroitin sulfate, diluting this aqueous solution with water, thereafter repeating the concentrating operation of chondroitin sulfate by ultrafiltration treatment, and either drying the concentrated liquid as it is obtained or depositing chondroitin sulfate by adding ethanol to the concentrated liquid obtained.;COPYRIGHT: (C)2000,JPO