PCT No. PCT/EP93/00850 Sec. 371 Date Feb. 2, 1994 Sec. 102(e) Date Feb. 2, 1994 PCT Filed Apr. 5, 1993 PCT Pub. No. WO93/20198 PCT Pub. Date Oct. 14, 1993The present invention discloses intersexual heterozygous Phycomyces strains. These strains show an improved beta -carotene productivity and an increased stability when compared with both the wild type and heterokaryotic Phycomyces strains. The present invention also discloses a method for obtaining Phycomyces transformants without using selection markers. Furthermore, a process is provided for manufacturing beta -carotene comprising the use of intersexual heterozygous Phycomyces strains in a submerged culture.
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