首页> 外国专利> COMPOSITIONS FOR INHIBITING THE PROLIFERATION OF HUMAN IMMUNODEFICIENCY VIRUS AND METHOD OF INHIBITING THE PROLIFERATION OF THIS VIRUS

COMPOSITIONS FOR INHIBITING THE PROLIFERATION OF HUMAN IMMUNODEFICIENCY VIRUS AND METHOD OF INHIBITING THE PROLIFERATION OF THIS VIRUS

机译:抑制人免疫缺陷病毒增殖的组合物和抑制该病毒增殖的方法

摘要

(+)-Proto-quercitol, (-)-proto-quercitol or (±)-proto-quercitol represented by the following formula (I-1): or L-epi-2-inosose, D-epi-2-inosose or DL-epi-2-inosose represented by the formula (I-2), have an activity of inhibiting the proliferation of HIV infecting human T cells and/or human monocytes/macrophages and/or other human hemocytes and, therefore, are useful as HIV proliferation inhibitors. Also, a method of inhibiting the proliferation of HIV by treating HIV with the compounds of the formula (I-1), the compounds of the formula (I-2) or enantiomers or racemates thereof is provided.
机译:由下式(I-1)表示的(+)-原槲皮醇,(-)-原槲皮醇或(±)-原-槲皮醇:或L-表-2-肌糖,D-表-2-肌糖由式(I-2)表示的或DL-epi-2-肌苷具有抑制HIV感染人T细胞和/或人单核细胞/巨噬细胞和/或其他人血细胞的增殖的活性,因此是有用的作为HIV扩散抑制剂。此外,提供了一种通过用式(I-1)的化合物,式(I-2)的化合物或其对映异构体或外消旋物治疗HIV来抑制HIV增殖的方法。

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