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COMPOUNDS OBTAINED FROM SALVIA SPECIES HAVING ANTIVIRAL ACTIVITY

机译:从鼠尾草属植物中获得的具有抗病毒活性的化合物

摘要

The present invention provides a composition containing a molecule having at least one residue from β- (3,4-dihydroxyphenyl) lactic acid and / or coffee acid found in an extract of plant genus Salvia, wherein the residue is of the formula Represented by I, the active agent has a molecular weight of at least 190 Daltons. Preferred types of reagents are those that combine to form dimers, trimers, tetramers and larger polymers containing these residues, most preferred are salvianolic acid dimers, trimers, tetramers and larger polymers. These compounds and compositions may be administered systemically or locally to pharmaceutically acceptable carriers and excipients to treat viral infections.;Formula I
机译:本发明提供了一种组合物,其包含在鼠尾草属植物的提取物中发现的具有至少一个来自β-(3,4-二羟基苯基)乳酸和/或咖啡酸的残基的分子,其中所述残基具有下式表示: ,该活性剂的分子量至少为190道尔顿。优选的试剂类型是那些结合形成包含这些残基的二聚体,三聚体,四聚体和较大的聚合物的试剂,最优选的是丹酚酸二聚体,三聚体,四聚体和较大的聚合物。这些化合物和组合物可以全身或局部施用于药学上可接受的载体和赋形剂,以治疗病毒感染。

著录项

  • 公开/公告号KR20010071580A

    专利类型

  • 公开/公告日2001-07-28

    原文格式PDF

  • 申请/专利权人 윌리암 제이.하트만;

    申请/专利号KR20007014664

  • 发明设计人 한면케이.;리폴;

    申请日2000-12-22

  • 分类号A61K31/192;

  • 国家 KR

  • 入库时间 2022-08-22 01:13:10

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